The Muddy River in Nevada is a short but ecologically significant waterway flowing approximately 32 miles through Clark County in southern Nevada's Mojave Desert. Originating from a series of thermal springs in the Moapa Valley, this spring-fed river maintains relatively stable flows and warm water temperatures year-round before emptying into the northern arm of Lake Mead near Overton. The river's clear, warm waters support both native endangered species and popular game fish, making it a unique fishing destination about 60 miles northeast of Las Vegas. The Muddy River flows through diverse terrain from its spring-fed headwaters through agricultural areas and eventually into Lake Mead, offering varied fishing opportunities along its course.