Mistletoe State Park offers year-round access to J. Strom Thurmond Reservoir with three boat ramps located throughout the day-use and camping areas, plus canoe rentals available at the park office.

The park features 92 RV-friendly campsites with electric and water hookups, a swimming beach, and eight hiking/biking trails, making it a well-equipped base for both paddling and fishing activities on the 71,000-acre lake.