Tweede Merwedehaven (2e Merwedehaven) is one of the major inland ports along the Beneden-Merwede in the municipality of Dordrecht, Netherlands.

Together with the 1e and 3e Merwedehaven, it ranks among the most significant inland harbors in the area, serving inland waterway vessels navigating the Beneden-Merwede and Oude Maas.

The harbor is situated within a broader industrial waterfront zone and is subject to ongoing redevelopment efforts by ROM-D in partnership with the gemeente Dordrecht.

The aim is to repurpose existing business terrain to accommodate waterway-dependent enterprises, including businesses relocating from Dordrecht's city center as well as companies from outside the Drechtsteden region seeking to establish a second location.