Upper Myrtle Lake Campground sits along the Entiat River Trail at approximately 3. 6 miles from the trailhead, offering established campsites on the south shore of Myrtle Lake with scenic granite-lined alpine views.

The location serves as a popular base camp for backpackers accessing the Glacier Peak Wilderness and higher alpine lakes (Larch and Ice Lakes), with shore access and shade available on the north side for day-use breaks.

Access requires hiking the Entiat River Trail and crossing the Entiat River via bridge or ford; a Northwest Forest Pass and wilderness permit (self-issued at trailhead) are required.