Indian Creek Campground is the largest campground on Mark Twain Lake with 190 electric campsites (20/30/50 amp service), 20 primitive hike-in tent sites, and a group campground, offering paved roads, clean bathhouses with showers, and playgrounds.

The recreation area features a public boat ramp, private swimming beach for campers, fish cleaning station, and extensive hiking and biking trails with lake access points.

Located on the northern banks of Mark Twain Lake near Monroe City, the campground is well-maintained with good tree coverage and privacy between sites, though reservations are recommended especially for weekends.