Hoyes Run serves as a take-out point for expert paddlers completing the Class V-VI "Top Yough" section of the Youghiogheny River, located near the Hoyes power station.

The area also provides access for hiking and fly fishing (catch and release only) along this remote and primitive stretch of Maryland's Wild and Scenic River.

Note that due to strict regulations and local property concerns, take-out should be done quickly and shuttle vehicles should not be left on private property.