Muddy Creek Access features a 20-foot wide concrete boat ramp with docks on both sides, ample parking, and ADA-accessible portable restrooms, making it an ideal launch point for the 53-mile Susquehanna River Water Trail. Located at River Mile 22.

3 near the historic Lock 15 area, this access point requires a PFBC Un-powered Boat Launch Permit or valid DCNR Launch Permit for paddlers.

The lake-like conditions of the Conowingo Reservoir in this section make it suitable for paddling year-round, with nearby alternative access points available for extended trips or breaks.