Horseshoe Bend Access provides a dead-end parking lot serving the 2,606-acre Horseshoe Bend Division of Port Louisa National Wildlife Refuge, located in the Iowa River floodplain approximately four miles upstream from its confluence with the Mississippi River.

The division features a unique mosaic of grassland, wet meadow, and seasonal wetland habitat that supports considerable migratory bird usage and provides opportunities for wildlife observation and photography.

Access is available from Wapello by taking Highway 99 east 1. 5 miles to 114th Street, then following the winding gravel road 3. 5 miles to F Avenue.