Santa Cruz Island Access is reached exclusively by boat through Island Packers concessionaire service from Ventura Harbor (approximately 1-1. 5 hours travel time), with advance ticket purchases strongly recommended as boats frequently sell out.

The island offers two primary landing sites—Scorpion Anchorage and Prisoners Harbor—with facilities including visitor centers, campgrounds, and water fill stations, supporting diverse recreational activities including hiking, kayaking, snorkeling, and wildlife viewing.

Visitors should plan accordingly as there is no food service on the island, no transportation once ashore, and all gear and trash must be carried in and out.