Prisoners Harbor is the main boat access point on Santa Cruz Island's north shore, offering a protected anchorage suitable for vessels and serving as the primary entry point for visitors arriving by boat.

The harbor features a cobblestone beach, a pier with dinghy dock access, and a new seven-site campground (completed Summer 2024) for overnight stays.

Access is by boat only from Santa Barbara or Ventura harbors, and all visits must be coordinated with Channel Islands National Park and follow biosecurity protocols; kayaking and snorkeling opportunities are available in the area, though eel grass and mud can affect anchoring conditions.