Heart Lake Access is located at the Mosquito Flat trailhead (10,224 feet elevation) in Little Lakes Valley, accessed via Rock Creek Road west of Bishop.

The trail is only 1 mile one-way with gentle grades, making it ideal for hikers of all abilities, though altitude acclimatization is strongly recommended.

Parking can fill quickly during peak times, with overflow areas available and a backpacker campground with 10 sites at the trailhead for one-night stays.