Waterhuizen is a small settlement in the province of Groningen where the Drentsche Diep meets the Winschoterdiep, an artificial waterway linking Groningen with Winschoten.

For paddlers and boaters traveling the Drentsche Diep, this confluence marks the end of the river's northward journey through a broad glacial valley shaped by ancient meltwater.

The Drentsche Diep itself winds through a quiet cultivated landscape of reed-fringed banks, pastures, and hay meadows before reaching Waterhuizen.

The river is the northern stretch of the Hunze system, carrying water from the Zuidlaardermeer down to this junction point, making Waterhuizen a natural access and exit point for anyone exploring the waterway by canoe, kayak, or small boat.