Killaloe sits on the southern shore of Lough Derg and serves as one of five named trailheads on the Lough Derg Way, a 64 km waymarked walking route that follows the River Shannon northwestwards from Limerick City to Dromineer.

The town is also one of 14 formal paddling access points around the lake, making it a practical launch spot for kayakers, canoeists, and stand-up paddleboarders exploring the Lough Derg Blueway.

Beyond its role as a trail gateway, Killaloe is a heritage town with notable historic character, including St Flannan's Cathedral and its early Christian oratory. It was once home to Brian Boru, the 11th-century High King of Ireland.

Parking is generally available near the access point, and the town offers pubs, cafes, and restaurants for post-activity refuelling.