The Río Grande is one of the principal tributaries forming the Limarí River system in the Coquimbo Region of Chile, draining a significant portion of the semi-arid Andean foothills and valleys of the IV Region. The river flows through a landscape shaped by the transition between the arid Norte Chico and the more temperate central Chilean valleys, passing through the communes of Monte Patria and contributing to the broader Limarí basin, which covers approximately 1,176,000 hectares — roughly 3% of the Coquimbo Region. The river and its watershed reflect the ecological character of this transitional zone, where water is a precious resource and the aquatic environment supports a small but ecologically significant community of native fish.