The DeSable River is a notable waterway on Prince Edward Island's southern side, flowing through a landscape that provides excellent habitat for a variety of fish species. Like many of PEI's rivers, the DeSable benefits from the island's characteristic terrain and its proximity to the Northumberland Strait, which allows sea-run fish to move in and out of the system seasonally. The river has earned a reputation among local anglers as a productive destination, particularly for those chasing migratory species that use the estuary and river corridor throughout the year.