Río Pescado winds through the rugged landscape of Salta Province in northwestern Argentina, flowing as part of the upper Río Bermejo basin. This remote river system drains a region of dramatic topographic and ecological diversity, characteristic of the transition zones found in the Salta highlands. The river's position within the Bermejo drainage gives it a distinct character shaped by the surrounding geology and the subtropical influences of the region, making it a notable waterway within Argentina's northwestern river network.