Calilegua National Park, situated about 106 km from San Salvador de Jujuy, protects over 76,000 hectares of Southern Andean Yungas — subtropical evergreen mountain rainforest recognized as one of Argentina's most biodiverse environments.

Established in 1979, the park spans elevations from roughly 400 to 3,000 meters on the eastern slopes of the Calilegua hills in Ledesma Department. The campground on Río San Lorenzo provides basic services including drinking water and bathrooms.

A separate camping area called Aguas Negras also offers similar facilities. Visitors are advised to notify park rangers before heading out on the trails. Wildlife watching, trekking, horseback riding, and mountain biking are among the main activities.

The park shelters more than 350 bird species along with pumas, jaguars, tapirs, capuchin monkeys, and peccaries. The picnic area at Mesada de las Colmenas, at 1,150 meters elevation, offers panoramic views of surrounding hills.

The park is open year-round, with April through October considered the ideal visiting period.