Río Carcarañá is a significant river system flowing through the agricultural heartland of central Argentina, originating at the confluence of the Río Tercero and the Saladillo River (also known as the lower course of the Río Cuarto) in the southeastern corner of Córdoba Province, near Cruz Alta. From there, it travels eastward into Santa Fe Province, covering a total length of approximately 240 kilometers (150 miles) before emptying into the Río Coronda south of Gaboto. The Coronda itself then joins the Paraná River roughly 7 kilometers below the Carcarañá's mouth. The river traverses one of the most productive agricultural regions in the world, passing through or near the cities and towns of Inriville, Los Surgentes, Cruz Alta, Arteaga, San José de la Esquina, Los Nogales, Arequito, Los Molinos, Casilda, Carcarañá, Andino, and Gaboto. The Carcarañá basin encompasses 2 percent of Santa Fe's territory and supports 4 percent of its population, making it an important regional waterway with a rich history of human use dating back to the 19th century.