Arroyo San Francisco is a tributary stream flowing through the Sierras Chicas mountain range in Córdoba Province, Argentina, forming part of the broader Suquía river basin. The stream passes through a series of charming sierra towns including Villa Giardino, Huerta Grande, Valle Hermoso, and Molinari, giving it a distinctly scenic character as it winds through forested hillsides and rocky terrain. As a highland arroyo fed by the surrounding sierras, it offers a classic small-stream fishing experience in a beautiful natural setting, with clear mountain waters and a diverse native fish community that has been the subject of scientific study since the late 1990s.